Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309485 | 0.95 | ALDH1A1 (0.41) | ACHEBCHEDRD2DRD4 | |
| SCHEMBL7303592 | 0.92 | ACHE (0.42) | CACNA1GACHEBCHEDRD2DRD4 | |
| SCHEMBL7308900 | 0.92 | ACHE (0.42) | ACHEBCHEDRD2DRD4 | |
| SCHEMBL7308778 | 0.91 | LTA4H (0.42) | CACNA1GACHEBCHE | |
| SCHEMBL7316449 | 0.91 | ACHE (0.43) | ACHEBCHEDRD2DRD4 | |
| SCHEMBL7314334 | 0.90 | CACNA1G (0.42) | CACNA1GDRD2DRD4 | |
| SCHEMBL7314139 | 0.90 | CACNA1G (0.42) | LMNAOPRM1OPRD1CACNA1G | |
| SCHEMBL7311499 | 0.90 | ACHE (0.42) | ACHEBCHEDRD2DRD4 | |
| SCHEMBL7310167 | 0.90 | CACNA1G (0.42) | CACNA1G | |
| SCHEMBL7316550 | 0.88 | ACHE (0.42) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |