Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.40 |
| ▸ | CTSS | P25774 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7314585 | 0.86 | AKT1 (0.47) | CTSKCTSSALDH1A1MEN1LMNA | |
| SCHEMBL7317918 | 0.78 | CTSK (0.46) | CTSKCTSSALDH1A1MEN1LMNA | |
| SCHEMBL7305458 | 0.78 | CTSK (0.46) | CTSKCTSSALDH1A1MEN1LMNA | |
| SCHEMBL7317017 | 0.76 | CTSK (0.47) | CTSKCTSSALDH1A1MEN1LMNA | |
| SCHEMBL8086805 | 0.76 | HTR2A (0.41) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL7311059 | 0.76 | CTSK (0.47) | CTSKCTSSALDH1A1MEN1LMNA | |
| SCHEMBL7307839 | 0.72 | ANPEP (0.49) | CTSKCTSSALDH1A1MEN1LMNA | |
| SCHEMBL7316663 | 0.71 | CA2 (0.53) | CTSKCTSSALDH1A1MEN1LMNA | |
| SCHEMBL7302612 | 0.70 | EBP (0.41) | LMNAMMP1MMP2MMP3MMP9 | |
| SCHEMBL6862901 | 0.70 | ALDH1A1 (0.51) | CTSKCTSSALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |