Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | FPR3 | P25089 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306902 | 0.93 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1CYP1A2L3MBTL1 | |
| SCHEMBL7304274 | 0.93 | SMN1; SMN2 (0.34) | GLASMN1; SMN2TSHRLMNA | |
| SCHEMBL7313690 | 0.91 | CYP1A2 (0.33) | SMN1; SMN2ALDH1A1LMNACYP1A2GAA | |
| SCHEMBL7317073 | 0.89 | MEN1 (0.33) | GLASMN1; SMN2ALDH1A1FPR3FPR2 | |
| SCHEMBL7307179 | 0.89 | OPRL1 (0.33) | PAOXGLASMN1; SMN2FPR3FPR2 | |
| SCHEMBL7311246 | 0.89 | DRD2 (0.35) | SMN1; SMN2ALDH1A1LMNARAD52 | |
| SCHEMBL7303867 | 0.89 | SMN1; SMN2 (0.38) | PAOXGLASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL7314139 | 0.87 | CACNA1G (0.42) | SMN1; SMN2TSHRALDH1A1LMNA | |
| SCHEMBL7313310 | 0.86 | MAOB (0.35) | SMN1; SMN2FPR3FPR2 | |
| SCHEMBL7316521 | 0.86 | SMN1; SMN2 (0.41) | SMN1; SMN2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |