Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7303823 | 0.93 | PAOX (0.35) | SMN1; SMN2ALDH1A1L3MBTL1CYP1A2 | |
| SCHEMBL7313690 | 0.93 | CYP1A2 (0.33) | SMN1; SMN2ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL7316521 | 0.92 | SMN1; SMN2 (0.41) | SMN1; SMN2TP53ALDH1A1KDM4EKDM1A | |
| SCHEMBL7308005 | 0.88 | GLA (0.39) | TP53ALDH1A1KDM4EL3MBTL1KDM1A | |
| SCHEMBL7315517 | 0.88 | SMN1; SMN2 (0.37) | SMN1; SMN2TP53ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL7313049 | 0.87 | SMN1; SMN2 (0.38) | SMN1; SMN2TP53ALDH1A1KDM4EKDM1A | |
| SCHEMBL7314712 | 0.87 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1KDM4EL3MBTL1KDM1A | |
| SCHEMBL7307041 | 0.87 | KMT2A (0.44) | ALDH1A1KDM4E | |
| SCHEMBL7304274 | 0.86 | SMN1; SMN2 (0.34) | SMN1; SMN2TP53 | |
| SCHEMBL7313193 | 0.84 | SIGMAR1 (0.33) | SMN1; SMN2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |