SCHEMBL7313310 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	MAOB	P27338	4/20	0.35

▸	KEAP1	Q14145	1/20	0.32

▸	NFE2L2	Q16236	1/20	0.32

▸	DAO	P14920	1/20	0.32

▸	FPR3	P25089	1/20	0.32

▸	FPR2	P25090	1/20	0.32

▸	SMN1; SMN2	Q16637	1/20	0.31

▸	HTR4	Q13639	1/20	0.31

▸	SIGMAR1	Q99720	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7306138	0.96	SMN1; SMN2 (0.36)	MAOBKEAP1NFE2L2DAOFPR3
SCHEMBL7305673	0.90	HRH3 (0.31)	KEAP1NFE2L2SMN1; SMN2HTR4SIGMAR1
SCHEMBL7317073	0.89	MEN1 (0.33)	FPR3FPR2SMN1; SMN2
SCHEMBL7314586	0.89	MAOB (0.37)	MAOBDAOSMN1; SMN2HTR4
SCHEMBL7311515	0.87	MAOB (0.37)	MAOBDAOSMN1; SMN2HTR4
SCHEMBL7307179	0.87	OPRL1 (0.33)	FPR3FPR2SMN1; SMN2HTR4SIGMAR1
SCHEMBL7303823	0.86	PAOX (0.35)	FPR3FPR2SMN1; SMN2
SCHEMBL7314564	0.85	SMN1; SMN2 (0.33)	MAOBKEAP1NFE2L2FPR3FPR2
SCHEMBL7300811	0.85	MAOB (0.37)	MAOBDAOHTR4SIGMAR1
SCHEMBL7314712	0.85	SMN1; SMN2 (0.38)	FPR3FPR2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0711770-A1	Antagonists of adhesion receptors	MERCK PATENT GmbH (DE)	1996-05-15	—	—	EP	disclosed