Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316521 | 0.94 | SMN1; SMN2 (0.41) | SMN1; SMN2GRIN2BTP53HSD17B10TSHR | |
| SCHEMBL7303823 | 0.93 | PAOX (0.35) | SMN1; SMN2GLATSHRLMNA | |
| SCHEMBL7316738 | 0.91 | GRIN1 (0.40) | CHRM2CHRM1GRIN1GRIN2BHSD17B10 | |
| SCHEMBL7313193 | 0.90 | SIGMAR1 (0.33) | SMN1; SMN2BRD4OPRM1HTR7 | |
| SCHEMBL7310298 | 0.90 | HTR4 (0.32) | SMN1; SMN2CHRM2CHRM1 | |
| SCHEMBL7313428 | 0.88 | CYP1A2 (0.37) | SMN1; SMN2CHRM2CHRM1GRIN1GRIN2B | |
| SCHEMBL7318029 | 0.87 | GRIN1 (0.40) | SMN1; SMN2CHRM2CHRM1GRIN1GRIN2B | |
| SCHEMBL7315016 | 0.87 | CHRM2 (0.38) | CHRM2CHRM1GRIN1GRIN2BHSD17B10 | |
| SCHEMBL7309020 | 0.87 | CHRM2 (0.38) | SMN1; SMN2CHRM2CHRM1GRIN1GRIN2B | |
| SCHEMBL7307179 | 0.86 | OPRL1 (0.33) | SMN1; SMN2GLACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |