Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309302 | 0.94 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL7315052 | 0.94 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1KMT2AMEN1DRD2 | |
| SCHEMBL7317129 | 0.92 | KMT2A (0.45) | SMN1; SMN2ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL7305487 | 0.91 | ALDH1A1 (0.42) | SMN1; SMN2ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL7314570 | 0.90 | CACNA1G (0.43) | SMN1; SMN2ALDH1A1KMT2ADRD2DRD4 | |
| SCHEMBL7313638 | 0.89 | ACHE (0.47) | — | |
| SCHEMBL7313953 | 0.88 | ACHE (0.45) | — | |
| SCHEMBL7316859 | 0.87 | ACHE (0.43) | SMN1; SMN2 | |
| SCHEMBL7304991 | 0.87 | ACHE (0.47) | — | |
| SCHEMBL7307041 | 0.86 | KMT2A (0.44) | ALDH1A1KMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |