Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 5/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311883 | 0.96 | HTR7 (0.43) | CACNA1GALDH1A1HTR7CHRM2CHRM4 | |
| SCHEMBL7309384 | 0.96 | CHRM2 (0.43) | CACNA1GALDH1A1HTR7CHRM2CHRM4 | |
| SCHEMBL7317129 | 0.94 | KMT2A (0.45) | ALDH1A1HTR7DRD2DRD4KMT2A | |
| SCHEMBL7311744 | 0.92 | HTR7 (0.43) | ALDH1A1HTR7CHRM2CHRM4CHRM5 | |
| SCHEMBL7307606 | 0.92 | CHRM2 (0.43) | CACNA1GALDH1A1HTR7CHRM2CHRM4 | |
| SCHEMBL7303537 | 0.91 | LTA4H (0.47) | — | |
| SCHEMBL7314139 | 0.91 | CACNA1G (0.42) | CACNA1GALDH1A1HTR7KMT2ASMN1; SMN2 | |
| SCHEMBL7307208 | 0.90 | LTA4H (0.49) | — | |
| SCHEMBL7303939 | 0.90 | SMN1; SMN2 (0.44) | ALDH1A1DRD2DRD4KMT2ASMN1; SMN2 | |
| SCHEMBL7308778 | 0.90 | LTA4H (0.42) | CACNA1G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |