Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7314518 | 0.94 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2TSHRKMT2AMEN1 | |
| SCHEMBL7314534 | 0.94 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2TSHRKMT2AMEN1 | |
| SCHEMBL7307041 | 0.93 | KMT2A (0.44) | ALDH1A1TSHRKMT2AMEN1MAPT | |
| SCHEMBL7314139 | 0.92 | CACNA1G (0.42) | ALDH1A1SMN1; SMN2TSHRKMT2AMEN1 | |
| SCHEMBL7303939 | 0.91 | SMN1; SMN2 (0.44) | ALDH1A1SMN1; SMN2TSHRKMT2AMEN1 | |
| SCHEMBL7309154 | 0.90 | ACHE (0.45) | ACHE | |
| SCHEMBL7317984 | 0.88 | ACHE (0.43) | ACHE | |
| SCHEMBL7314334 | 0.88 | CACNA1G (0.42) | ALDH1A1SMN1; SMN2TSHRKMT2AMEN1 | |
| SCHEMBL7310167 | 0.88 | CACNA1G (0.42) | ALDH1A1SMN1; SMN2TSHRKMT2AMEN1 | |
| SCHEMBL7309596 | 0.88 | ALDH1A1 (0.43) | ALDH1A1TSHRKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |