SCHEMBL7304026

SCHEMBL7304026

Cc1cc2c(cc1[N+](=O)[O-])CC(CCCCC(=O)C1C(=S)CN[C@@H]1C(=O)N1CCSC1)C2

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 4/20 0.34
PREP P48147 2/20 0.31
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
DPP8 Q6V1X1 1/20 0.30
DPP9 Q86TI2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7304031 0.86 DPP4 (0.35) DPP4PREPALDH1A1MAPTSMN1; SMN2
SCHEMBL7300887 0.80 PREP (0.46) DPP4PREPDPP8DPP9
SCHEMBL7296683 0.72 PREP (0.52) DPP4PREPDPP8DPP9
SCHEMBL7305071 0.71 PREP (0.51) DPP4PREPDPP8DPP9
SCHEMBL7292258 0.69 PNMT (0.43)
SCHEMBL7291297 0.68 PREP (0.49) DPP4PREP
SCHEMBL7297854 0.68 PREP (0.57) DPP4PREPDPP8DPP9
SCHEMBL7301347 0.68 PREP (0.57) DPP4PREPDPP8DPP9
SCHEMBL7295937 0.68 PREP (0.57) DPP4PREPDPP8DPP9
SCHEMBL7303628 0.67 DPP4 (0.38) DPP4PREPDPP8DPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0372484-B1 Condensed benzene derivative ZERIA PHARM CO LTD (JP) 1994-10-26 EP disclosed
US-5028604-A Cognition Activators ZERIA PHARMACEUTICAL CO., LTD. (JP) 1991-07-02 US disclosed
EP-0372484-A2 Condensed benzene derivative ZERIA PHARMACEUTICAL CO., LTD. (JP) 1990-06-13 EP disclosed