Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.35 |
| ▸ | PREP | P48147 | 6/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7304026 | 0.86 | DPP4 (0.34) | DPP4PREPALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7300891 | 0.79 | PREP (0.48) | DPP4PREPDPP8DPP9 | |
| SCHEMBL7305077 | 0.71 | PREP (0.53) | DPP4PREPDPP8DPP9 | |
| SCHEMBL8154287 | 0.67 | PREP (0.60) | DPP4PREPDPP8DPP9 | |
| SCHEMBL7292264 | 0.67 | PNMT (0.43) | PREPALDH1A1MAPT | |
| SCHEMBL7295946 | 0.67 | PREP (0.60) | DPP4PREPDPP8DPP9 | |
| SCHEMBL8155765 | 0.67 | PREP (0.60) | DPP4PREPDPP8DPP9 | |
| SCHEMBL7291303 | 0.67 | PREP (0.51) | DPP4PREP | |
| SCHEMBL7304152 | 0.67 | LMNA (0.34) | PREPALDH1A1SMN1; SMN2 | |
| SCHEMBL7303635 | 0.66 | DPP4 (0.39) | DPP4PREPDPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372484-B1 | Condensed benzene derivative | ZERIA PHARM CO LTD (JP) | 1994-10-26 | — | — | EP | disclosed |
| EP-0372484-A2 | Condensed benzene derivative | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1990-06-13 | — | — | EP | disclosed |