Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PKLR | P30613 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7270697 | 0.90 | PKM (0.38) | PKMPTGES2MEN1KMT2ARAD52 | |
| SCHEMBL7268479 | 0.77 | LMNA (0.39) | PKMMEN1KMT2ANPC1PKLR | |
| SCHEMBL11120861 | 0.75 | PARP1 (0.60) | PARP1 | |
| SCHEMBL9485086 | 0.74 | DRD2 (0.64) | DRD2 | |
| SCHEMBL9485123 | 0.72 | DRD2 (0.75) | DRD2 | |
| SCHEMBL27950240 | 0.72 | PKM (0.57) | PKMPTGES2KMT2ANPC1PKLR | |
| SCHEMBL7270099 | 0.68 | KDM4E (0.40) | MEN1KMT2ADRD2 | |
| SCHEMBL2424255 | 0.68 | PTGES2 (0.65) | PKMPTGES2KMT2ANPC1PKLR | |
| SCHEMBL25387545 | 0.67 | ALDH1A1 (0.43) | PTGES2MEN1KMT2AGAA | |
| SCHEMBL7270768 | 0.67 | DRD2 (0.51) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407137-A2 | Benzazine compounds and pharmaceutical uses thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-01-09 | — | — | EP | disclosed |