Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7315016 | 0.95 | CHRM2 (0.38) | CHRM2CHRM1HTR7GRIN1GRIN2B | |
| SCHEMBL7309115 | 0.95 | HTR7 (0.38) | CHRM2CHRM1HTR7SMN1; SMN2GRIN1 | |
| SCHEMBL7316738 | 0.92 | GRIN1 (0.40) | CHRM2CHRM1HTR7GRIN1GRIN2B | |
| SCHEMBL7307085 | 0.91 | SIGMAR1 (0.38) | CHRM2CHRM1HTR7TSHRHSD17B10 | |
| SCHEMBL7308518 | 0.90 | CHRM2 (0.36) | CHRM2CHRM1HTR7SMN1; SMN2GRIN1 | |
| SCHEMBL7310298 | 0.90 | HTR4 (0.32) | CHRM2CHRM1SMN1; SMN2 | |
| SCHEMBL7305895 | 0.90 | CHRM2 (0.39) | CHRM2CHRM1HTR7SMN1; SMN2GRIN1 | |
| SCHEMBL7318029 | 0.88 | GRIN1 (0.40) | CHRM2CHRM1HTR7SMN1; SMN2GRIN1 | |
| SCHEMBL7304274 | 0.87 | SMN1; SMN2 (0.34) | CHRM2CHRM1HTR7SMN1; SMN2GRIN1 | |
| SCHEMBL7305673 | 0.86 | HRH3 (0.31) | CHRM2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |