Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 10/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | FAP | Q12884 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ADAM10 | O14672 | 2/20 | 0.30 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7304402 | 0.82 | PREP (0.35) | PREPDPP4FAPLMNAMAPT | |
| SCHEMBL7302998 | 0.82 | DPP4 (0.42) | PREPDPP4FAPADAM10ERBB2 | |
| SCHEMBL8153717 | 0.80 | PREP (0.57) | PREP | |
| SCHEMBL7294247 | 0.80 | PREP (0.57) | PREP | |
| SCHEMBL8154403 | 0.80 | PREP (0.57) | PREP | |
| SCHEMBL7440061 | 0.77 | CYP26A1 (0.44) | PREPDPP4 | |
| SCHEMBL7296377 | 0.74 | DPP4 (0.42) | PREPDPP4FAP | |
| SCHEMBL7293165 | 0.74 | PREP (0.40) | PREPADAM10ERBB2MMP2 | |
| SCHEMBL7292264 | 0.72 | PNMT (0.43) | PREPMAPTHPGD | |
| SCHEMBL7437576 | 0.71 | ALDH1A1 (0.43) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6017929-A | Cholinesterase activator | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2000-01-25 | — | — | US | disclosed |
| EP-0754454-A1 | CHOLINESTERASE ACTIVATOR | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-22 | — | — | EP | disclosed |
| EP-0372484-B1 | Condensed benzene derivative | ZERIA PHARM CO LTD (JP) | 1994-10-26 | — | — | EP | disclosed |
| US-5028604-A | Cognition Activators | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0372484-A2 | Condensed benzene derivative | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1990-06-13 | — | — | EP | disclosed |