Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.38 |
| ▸ | FBP1 | P09467 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7304680 | 1.00 | NR1I2 (0.44) | NR1I2KDM1AMEN1KMT2AALDH1A1 | |
| SCHEMBL59713 | 0.87 | KDM1A (0.48) | NR1I2KDM1AMEN1KMT2AALDH1A1 | |
| SCHEMBL8467955 | 0.87 | FBP1 (0.42) | NR1I2MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL7292401 | 0.84 | LMNA (0.45) | NR1I2KDM1AMEN1KMT2AALDH1A1 | |
| SCHEMBL7292404 | 0.84 | LMNA (0.45) | NR1I2KDM1AMEN1KMT2AALDH1A1 | |
| SCHEMBL28293058 | 0.81 | TRPA1 (0.52) | NR1I2KDM1AMEN1KMT2AALDH1A1 | |
| SCHEMBL28472907 | 0.81 | TRPA1 (0.52) | NR1I2KDM1AMEN1KMT2AALDH1A1 | |
| SCHEMBL6859832 | 0.80 | LMNA (0.57) | MEN1KMT2ALMNATDP1NPC1 | |
| SCHEMBL9312061 | 0.79 | LMNA (0.47) | NR1I2KDM1AMEN1KMT2AALDH1A1 | |
| SCHEMBL17329401 | 0.79 | KDM1A (0.47) | NR1I2KDM1AMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347766-B1 | 4,5,7,8-Tetrahydro-6H-thiazolo[5,4-d]azepines, their preparation and their use as medicaments | THOMAE GMBH DR K (DE) | 1994-05-25 | — | — | EP | disclosed |
| US-5068325-A | Dopaminergic systems as hypotensives, sedatives, antitussives and/or antiphlogistics | KARL THOMAE GMBH (DE) | 1991-11-26 | — | — | US | disclosed |
| EP-0347766-A2 | 4,5,7,8-Tetrahydro-6H-thiazolo[5,4-d]azepines, their preparation and their use as medicaments | Dr. Karl Thomae GmbH (DE) | 1989-12-27 | — | — | EP | disclosed |
| EP-0108627-A2 | Cephalosporin derivatives and process for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-05-16 | — | — | EP | disclosed |