SCHEMBL8467955

SCHEMBL8467955

ClCC(=Cc1ccccc1)CCl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 3/20 0.42
ALDH1A1 P00352 3/20 0.41
TSHR P16473 1/20 0.41
AKR1C3 P42330 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
AKR1C1 Q04828 1/20 0.40
ESR1 P03372 1/20 0.40
RECQL P46063 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
TRPA1 O75762 1/20 0.39
MAPK1 P28482 1/20 0.39
GSK3B P49841 1/20 0.39
HIF1A Q16665 1/20 0.39
NR1I2 O75469 1/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
PRMT1 Q99873 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7304675 0.87 NR1I2 (0.44) FBP1ALDH1A1TSHRAKR1C3CYP3A4
SCHEMBL7304680 0.87 NR1I2 (0.44) FBP1ALDH1A1TSHRAKR1C3CYP3A4
SCHEMBL28379575 0.85 CYP3A4 (0.52) FBP1ALDH1A1TSHRAKR1C3CYP3A4
SCHEMBL7292404 0.83 LMNA (0.45) FBP1ALDH1A1TSHRAKR1C3RECQL
SCHEMBL7292401 0.83 LMNA (0.45) FBP1ALDH1A1TSHRAKR1C3RECQL
SCHEMBL6859832 0.79 LMNA (0.57) MEN1KMT2ANPC1RAB9ALMNA
SCHEMBL9296651 0.78 FBP1 (0.45) FBP1ALDH1A1TSHRAKR1C3CYP3A4
SCHEMBL4879220 0.78 TDP1 (0.58) ALDH1A1MEN1KMT2ANPC1RAB9A
SCHEMBL216869 0.77 TSHR (0.43) FBP1ALDH1A1TSHRAKR1C3CYP3A4
SCHEMBL5655358 0.76 ALDH1A1 (0.48) FBP1ALDH1A1TSHRAKR1C3RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112456468-A Preparation method of coal tar pitch-based carbon material with controllable microscopic morphology 大连理工大学 2021-03-09 CN claimed
US-4192920-A Uniform polymer beads and ion exchange resins therefrom prepared by post-crosslinking of lightly crosslinked beads ROHM AND HAAS COMPANY (US) 1980-03-11 US claimed
US-4191814-A POLYCHLOROMETHYLSTYRENE, POLY-TERT-AMINE ROHM AND HAAS COMPANY (US) 1980-03-04 US claimed
US-4093567-A Aminated crosslinked copolymers of bis(chloromethyl) styrene which exhibit improved anion exchange properties ROHM AND HAAS COMPANY (US) 1978-06-06 US claimed
CN-112456468-B Preparation method of coal tar pitch-based carbon material with controllable microscopic morphology 大连理工大学 2022-05-20 CN disclosed
CN-112456468-A Preparation method of coal tar pitch-based carbon material with controllable microscopic morphology 大连理工大学 2021-03-09 CN disclosed
CN-111819219-A Process for producing poly (vinylbenzyl) ether compound 第一工业制药株式会社 2020-10-23 CN disclosed
CN-106715576-B Composition for thermoplastic elastomer and molded product 株式会社可乐丽 2019-04-16 CN disclosed
CN-106661309-B Composition for thermoplastic elastomer 株式会社可乐丽 2019-04-16 CN disclosed
US-5965640-A A CROSSLINKABLE ACRYLIC RUBBER COMPRISES A HALOGEN CONTAINING ACRYLIC RUBBER, A TRIAZINE THIOL, DITHIOCARBAMINE ACID DERIVATIVE OR THIURAM SULFIDE OR BOTH, AN AROMATIC CARBOXYLIC ACID OR AN ACID ANHYDRIDE, WHITE FILLER AND SILANE COUPLER JSR CORPORATION (JP) 1999-10-12 US disclosed
EP-0811659-A2 Acrylic rubber composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1997-12-10 EP disclosed
US-4587203-A USING A DEVELOPMENT SOLVENT AND RINSING NONSOLVENT; SILANE COUPLING INTERLAYER; DIMENSIONAL STABILITY AND SHARPNESS OF IMAGE HUGHES AIRCRAFT COMPANY (US) 1986-05-06 US disclosed
US-4273878-A SUSPENSION POLYMERIZED POLY(CHLOROMETHYLSTYRENE), AMINATION-QUATERNIZATION, UNIFORM BEADS ROHM AND HAAS COMPANY (US) 1981-06-16 US disclosed
EP-0009361-A1 2-Alkoxycarbonylamino benzimidazoles having a halogen-containing substituent, their preparation and their use as parasiticides MERCK & CO. INC. (US) 1980-04-02 EP disclosed
US-4192920-A Uniform polymer beads and ion exchange resins therefrom prepared by post-crosslinking of lightly crosslinked beads ROHM AND HAAS COMPANY (US) 1980-03-11 US disclosed
US-4192920-A Uniform polymer beads and ion exchange resins therefrom prepared by post-crosslinking of lightly crosslinked beads ROHM AND HAAS COMPANY (US) 1980-03-11 US disclosed
US-4191814-A POLYCHLOROMETHYLSTYRENE, POLY-TERT-AMINE ROHM AND HAAS COMPANY (US) 1980-03-04 US disclosed
US-4093567-A Aminated crosslinked copolymers of bis(chloromethyl) styrene which exhibit improved anion exchange properties ROHM AND HAAS COMPANY (US) 1978-06-06 US disclosed
US-4093567-A Aminated crosslinked copolymers of bis(chloromethyl) styrene which exhibit improved anion exchange properties ROHM AND HAAS COMPANY (US) 1978-06-06 US disclosed
US-4093567-A Aminated crosslinked copolymers of bis(chloromethyl) styrene which exhibit improved anion exchange properties ROHM AND HAAS COMPANY (US) 1978-06-06 US disclosed