Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9800442 | 1.00 | FAAH (0.50) | FAAHHPGDACELMNAPKM | |
| SCHEMBL9800485 | 0.82 | FAAH (0.51) | FAAHMGLLTDP1 | |
| SCHEMBL11800230 | 0.82 | TSHR (0.64) | FAAHHPGDLMNAPKMSMN1; SMN2 | |
| SCHEMBL7302270 | 0.79 | PPARG (0.48) | HPGDLMNAPKMSMN1; SMN2PPARG | |
| SCHEMBL21706782 | 0.79 | FAAH (0.54) | FAAHHPGDLMNAPKMSMN1; SMN2 | |
| Acetic Acid SCHEMBL28974131 | 0.79 | TSHR (0.60) | FAAHHPGDLMNAPKMSMN1; SMN2 | |
| SCHEMBL27741870 | 0.79 | FAAH (0.54) | FAAHHPGDLMNAPKMSMN1; SMN2 | |
| SCHEMBL29743339 | 0.78 | FAAH (0.51) | FAAHHPGDLMNAPKMSMN1; SMN2 | |
| SCHEMBL8444601 | 0.78 | ADRB2 (0.44) | FAAHHPGDACELMNAPKM | |
| SCHEMBL23260954 | 0.77 | TSHR (0.62) | FAAHLMNASMN1; SMN2HDAC3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520336-A2 | Aldehyde derivatives and their use as calpain inhibitors | FUJIREBIO Inc. (JP) | 1992-12-30 | — | — | EP | disclosed |