Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 3/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31384049 | 0.85 | ADRB2 (0.49) | ADRB2ADRB1ADRB3SIGMAR1HPGD | |
| SCHEMBL7304728 | 0.78 | FAAH (0.50) | ADRB2ADRB1ADRB3HPGDFAAH | |
| SCHEMBL9800442 | 0.78 | FAAH (0.50) | ADRB2ADRB1ADRB3HPGDFAAH | |
| SCHEMBL10238709 | 0.74 | ATM (0.56) | SYKCTSKCTSSATMACE | |
| SCHEMBL2736627 | 0.74 | ATM (0.56) | SYKCTSKCTSSATMACE | |
| SCHEMBL7832583 | 0.74 | ADRB2 (0.41) | ADRB2ADRB1ADRB3HPGDFAAH | |
| SCHEMBL10578604 | 0.72 | HDAC1 (0.56) | ADRB2ADRB1ADRB3SIGMAR1HPGD | |
| SCHEMBL6961625 | 0.72 | SYK (0.47) | SYKCTSKCTSSATMACE | |
| SCHEMBL17844769 | 0.72 | ADRB2 (0.49) | ADRB2ADRB1ADRB3SIGMAR1CTSK | |
| SCHEMBL18085403 | 0.72 | CTSK (0.54) | SIGMAR1HPGDSYKCTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869786-A4 | PHARMACEUTICAL COMPOUNDS | LILLY CO ELI (US) | 1999-04-14 | — | — | EP | disclosed |
| EP-0869786-A1 | PHARMACEUTICAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997023211-A1 | PHARMACEUTICAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 1997-07-03 | — | — | WO | disclosed |