Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 13/20 | 0.37 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7298076 | 0.78 | NR1I3 (0.41) | — | |
| SCHEMBL7303281 | 0.77 | PGR (0.40) | PPARD | |
| SCHEMBL7306389 | 0.75 | MEN1 (0.35) | ACHEAKR1C4AKR1C3AKR1C2 | |
| SCHEMBL7300393 | 0.74 | AKR1C4 (0.42) | ACHEAKR1C4AKR1C3AKR1C2PPARD | |
| SCHEMBL7302144 | 0.73 | ITGB3 (0.49) | — | |
| Hydrochloric Acid SCHEMBL7302244 | 0.73 | AKR1C4 (0.41) | ACHEAKR1C4AKR1C3AKR1C2PPARD | |
| SCHEMBL7306751 | 0.72 | RXRA (0.44) | — | |
| SCHEMBL7301241 | 0.71 | MEN1 (0.37) | ACHEAKR1C4AKR1C3AKR1C2 | |
| SCHEMBL25247020 | 0.71 | BRD4 (0.43) | ACHEBRD4CREBBPPAX8 | |
| SCHEMBL30476644 | 0.71 | BRD4 (0.43) | ACHEBRD4CREBBPPAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709370-B1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5629321-A | FIBRINOGEN ANTAGONIST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0709370-A1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-01 | — | — | EP | disclosed |