Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 14/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 14/20 | 0.42 |
| ▸ | F2 | P00734 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7302144 | 0.85 | ITGB3 (0.49) | ITGB3ITGA2B | |
| SCHEMBL7307229 | 0.79 | ITGB3 (0.60) | RXRARXRBRXRGITGB3ITGA2B | |
| SCHEMBL7300114 | 0.78 | ITGB3 (0.47) | ITGB3ITGA2B | |
| SCHEMBL7303281 | 0.74 | PGR (0.40) | — | |
| SCHEMBL7300393 | 0.73 | AKR1C4 (0.42) | — | |
| SCHEMBL7304733 | 0.72 | ACHE (0.37) | — | |
| Hydrochloric Acid SCHEMBL7302244 | 0.72 | AKR1C4 (0.41) | — | |
| SCHEMBL7298694 | 0.70 | ITGB3 (0.47) | ITGB3ITGA2B | |
| SCHEMBL7306389 | 0.70 | MEN1 (0.35) | ITGB3ITGA2B | |
| SCHEMBL7301241 | 0.68 | MEN1 (0.37) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709370-B1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5629321-A | FIBRINOGEN ANTAGONIST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0709370-A1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-01 | — | — | EP | disclosed |