Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 4/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.30 |
| ▸ | HRH2 | P25021 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310042 | 0.82 | FAAH (0.32) | CHRM3CHRM2CHRM1 | |
| SCHEMBL7313602 | 0.79 | KCNH2 (0.37) | CHRM3KCNH2KIF11MRGPRX2HRH2 | |
| SCHEMBL7316634 | 0.72 | ALDH1A1 (0.39) | CHRM3CHRM2CHRM1 | |
| SCHEMBL7309814 | 0.71 | ALDH1A1 (0.38) | CHRM3CHRM2CHRM1KCNH2KIF11 | |
| SCHEMBL7304839 | 0.70 | CACNA1G (0.44) | KCNH2 | |
| SCHEMBL8837042 | 0.70 | LMNA (0.36) | CHRM3CHRM2CHRM1KCNH2KIF11 | |
| SCHEMBL7307228 | 0.70 | EBP (0.55) | CHRM3CHRM2CHRM1KCNH2HRH2 | |
| SCHEMBL7309620 | 0.70 | TAAR1 (0.36) | CHRM3CHRM2CHRM1KCNH2KIF11 | |
| SCHEMBL7307357 | 0.69 | ALDH1A1 (0.42) | CHRM3KCNH2KIF11MRGPRX2HRH2 | |
| SCHEMBL7317285 | 0.69 | CHRM3 (0.33) | CHRM3CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |