Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 9/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 8/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | PHGDH | O43175 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7304374 | 0.81 | HPGD (0.40) | DPP4DPP7HPGDALDH1A1 | |
| SCHEMBL7346646 | 0.79 | ALDH1A1 (0.41) | DPP4DPP7HPGDALDH1A1 | |
| SCHEMBL1911508 | 0.79 | DPP4 (0.44) | DPP4DPP7DPP8DPP9HPGD | |
| SCHEMBL7299020 | 0.78 | CYP1A2 (0.46) | HPGDALDH1A1HSD17B10 | |
| SCHEMBL6945616 | 0.77 | DPP4 (0.43) | DPP4DPP7DPP8DPP9HPGD | |
| SCHEMBL7299462 | 0.76 | SMN1; SMN2 (0.47) | HPGDALDH1A1HSD17B10 | |
| SCHEMBL7303416 | 0.76 | CA2 (0.42) | HPGDALDH1A1 | |
| SCHEMBL9019591 | 0.75 | DPP4 (0.42) | DPP4DPP7DPP8DPP9HPGD | |
| SCHEMBL18722240 | 0.75 | DPP4 (0.50) | DPP4DPP7DPP8DPP9HPGD | |
| SCHEMBL16435175 | 0.72 | DPP4 (0.51) | DPP4DPP7DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0594540-B1 | Antiretroviral acyl compounds | CIBA GEIGY AG (CH) | 1998-04-01 | — | — | EP | disclosed |
| EP-0594540-A1 | Antiretroviral acyl compounds | CIBA-GEIGY AG (CH) | 1994-04-27 | — | — | EP | disclosed |