Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CHKA | P35790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7304374 | 0.98 | HPGD (0.40) | ALDH1A1HTTMMP1MMP2MMP8 | |
| SCHEMBL7299020 | 0.81 | CYP1A2 (0.46) | ALDH1A1HPGDNPC1 | |
| SCHEMBL27651069 | 0.81 | ALDH1A1 (0.40) | ALDH1A1HTTMMP1MMP2MMP8 | |
| SCHEMBL7299462 | 0.79 | SMN1; SMN2 (0.47) | ALDH1A1HTTHPGDMAPTGAA | |
| SCHEMBL7303416 | 0.79 | CA2 (0.42) | ALDH1A1HPGDCA2CHKA | |
| SCHEMBL7305057 | 0.79 | DPP4 (0.40) | ALDH1A1HPGDDPP7DPP4 | |
| SCHEMBL5559398 | 0.78 | HPGD (0.39) | ALDH1A1HTTMMP1MMP2MMP8 | |
| SCHEMBL25447805 | 0.77 | ALDH1A1 (0.48) | ALDH1A1HTTMMP1MMP2MMP8 | |
| SCHEMBL8014381 | 0.77 | ALDH1A1 (0.48) | ALDH1A1HTTMMP1MMP2MMP8 | |
| SCHEMBL21455835 | 0.77 | ALDH1A1 (0.48) | ALDH1A1HTTMMP1MMP2MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6008228-A | COMPRISING A MIXTURE OF CARRIER MONOGLYCERIDES OF MEDIUM CHAIN-FATTY ACIDS | HOFFMAN-LA ROCHE INC. (US) | 1999-12-28 | — | — | US | disclosed |
| EP-0831826-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A PROTEINASE INHIBITOR AND A MONOGLYCERIDE | F. HOFFMANN-LA ROCHE AG (CH) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996039142-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A PROTEINASE INHIBITOR AND A MONOGLYCERIDE | F. HOFFMANN-LA ROCHE AG (CH) | 1996-12-12 | — | — | WO | disclosed |