Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29926166 | 0.98 | CA12 (0.39) | CA12CA7CA14SMN1; SMN2PKM | |
| SCHEMBL49152 | 0.98 | CA12 (0.39) | CA12CA7CA14SMN1; SMN2PKM | |
| SCHEMBL5492640 | 0.96 | CA12 (0.38) | CA12CA7CA14SMN1; SMN2PKM | |
| SCHEMBL29027428 | 0.96 | CA12 (0.38) | CA12CA7CA14SMN1; SMN2PKM | |
| SCHEMBL4566523 | 0.96 | CA12 (0.38) | CA12CA7CA14SMN1; SMN2PKM | |
| Hydrochloric Acid SCHEMBL28285547 | 0.94 | CA12 (0.37) | CA12CA7CA14SMN1; SMN2PKM | |
| SCHEMBL62393 | 0.82 | KDM4E (0.32) | LMNAKDM4EGAA | |
| SCHEMBL15572838 | 0.78 | CA12 (0.41) | CA12CA7CA14SMN1; SMN2PKM | |
| SCHEMBL4694756 | 0.78 | CA12 (0.41) | CA12CA7CA14SMN1; SMN2PKM | |
| Water SCHEMBL28800260 | 0.78 | KDM4E (0.30) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120079438-A | Integrated catalyst for coenzyme regeneration and preparation method thereof | 天津大学 | 2025-06-03 | — | — | CN | claimed |
| CN-119241129-B | High permeable concrete additive and permeable concrete | 重庆市武隆区交通工程有限责任公司 | 2025-05-30 | — | — | CN | claimed |
| CN-118914314-B | Quantitative determination method for metastable iron oxide vacancy defect concentration | 华中农业大学 | 2025-05-06 | — | — | CN | claimed |
| CN-119455149-A | Epoxy group modified zwitterionic polymer/heparin composite coating and preparation method thereof | 陕西科技大学 | 2025-02-18 | — | — | CN | claimed |
| CN-119241129-A | High permeable concrete additive and permeable concrete | 重庆市武隆区交通工程有限责任公司 | 2025-01-03 | — | — | CN | claimed |
| CN-118491564-A | Integrated catalyst for coenzyme regeneration and preparation method thereof | 天津大学 | 2024-08-16 | — | — | CN | claimed |
| CN-118501433-A | Color latex chromatography detection method and detection kit for respiratory syncytial virus and adenovirus | 广州华澳生物科技有限公司 | 2024-08-16 | — | — | CN | claimed |
| CN-117860900-B | Preparation method of slow-release type fructose calcium diphosphate | 张家港市华天药业有限公司 | 2024-07-23 | — | — | CN | claimed |
| CN-118303424-A | Application of silicon dioxide nano pesticide in preventing and treating plant diseases | 武汉科技大学 | 2024-07-09 | — | — | CN | claimed |
| CN-117860900-A | Preparation method of slow-release type fructose calcium diphosphate | 张家港市华天药业有限公司 | 2024-04-12 | — | — | CN | claimed |
| CN-114432459-B | Peroxidase nano-glucose oxidase double-enzyme complex, preparation method and application thereof | 吉林大学 | 2024-02-23 | — | — | CN | claimed |
| CN-117344456-A | Method for preparing sodium alginate electrospun nanofiber by adopting photo-crosslinking | 青岛大学 | 2024-01-05 | — | — | CN | claimed |
| CN-116726260-A | Coating, vascular implant material with coating, preparation method and application | 郑州大学 | 2023-09-12 | — | — | CN | claimed |
| CN-108865086-A | A kind of high inhibition, strong rubber knot borehole wall stabilizer and preparation method thereof | 中石化石油工程技术服务有限公司 | 2018-11-23 | — | — | CN | claimed |
| CN-119553490-B | Sericin in-situ reduction silver-loaded PET fiber and preparation method and application thereof | 安徽农业大学 | 2025-06-13 | — | — | CN | disclosed |
| CN-120079438-A | Integrated catalyst for coenzyme regeneration and preparation method thereof | 天津大学 | 2025-06-03 | — | — | CN | disclosed |
| CN-119241129-B | High permeable concrete additive and permeable concrete | 重庆市武隆区交通工程有限责任公司 | 2025-05-30 | — | — | CN | disclosed |
| EP-1919492-A2 | GROWTH HORMONE SECRETAGOGUES | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES S.A.S. (FR) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007068489-A2 | A MOLDABLE BIOMATERIAL FOR BONE REGENERATION | SCIL TECHNOLOGY GMBH (DE) | 2007-06-21 | — | — | WO | disclosed |
| WO-2007014258-A2 | GROWTH HORMONE SECRETAGOGUES | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES S.A.S. (FR) | 2007-02-01 | — | — | WO | disclosed |