Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.45 |
| ▸ | TACR1 | P25103 | 2/20 | 0.44 |
| ▸ | CTSB | P07858 | 2/20 | 0.43 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29398620 | 0.84 | CTSL (0.51) | CTSLITGB3ITGA2BCTSS | |
| SCHEMBL7355009 | 0.84 | CTSL (0.51) | CTSLITGB3ITGA2BCTSS | |
| SCHEMBL7304357 | 0.81 | SLC15A1 (0.36) | CTSL | |
| SCHEMBL8216035 | 0.80 | CTSL (0.49) | CTSLITGB3ITGA2BTACR1CTSB | |
| SCHEMBL9658435 | 0.78 | SLC1A1 (0.44) | CTSL | |
| SCHEMBL7296919 | 0.78 | LTA4H (0.38) | CTSL | |
| SCHEMBL9817992 | 0.78 | CTSL (0.69) | CTSLITGB3ITGA2BTACR1CTSS | |
| SCHEMBL8203294 | 0.77 | CTSL (0.44) | CTSLITGB3ITGA2BF2 | |
| SCHEMBL7296710 | 0.77 | NOS3 (0.47) | CTSL | |
| SCHEMBL29913526 | 0.76 | CTSL (0.53) | CTSLITGB3ITGA2BTACR1CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526877-A2 | Peptide aldehydes as antithrombotic agents | Bristol-Myers Squibb Company (US) | 1993-02-10 | — | — | EP | claimed |