Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.42 |
| ▸ | TACR1 | P25103 | 2/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4630111 | 0.88 | SLC6A2 (0.45) | OPRM1SLC6A3SLC6A4SLC6A2TACR1 | |
| SCHEMBL7745898 | 0.87 | POLB (0.39) | OPRM1SLC6A3SLC6A4SLC6A2TACR1 | |
| SCHEMBL374107 | 0.83 | OPRM1 (0.46) | OPRM1SLC6A3SLC6A4SLC6A2TACR1 | |
| SCHEMBL7305712 | 0.81 | OPRM1 (0.53) | OPRM1SLC6A3SLC6A4SLC6A2TACR1 | |
| SCHEMBL4630753 | 0.81 | OPRM1 (0.56) | OPRM1SLC6A3SLC6A4SLC6A2TACR1 | |
| SCHEMBL7306023 | 0.79 | CACNA1G (0.52) | OPRM1OPRL1KCNA3OPRD1OPRK1 | |
| SCHEMBL8064379 | 0.78 | OPRM1 (0.47) | OPRM1SLC6A3SLC6A4SLC6A2TACR1 | |
| SCHEMBL8041537 | 0.77 | SLC6A4 (0.69) | OPRM1SLC6A3SLC6A4SLC6A2TACR1 | |
| SCHEMBL7749119 | 0.76 | CYP2C19 (0.40) | OPRM1SLC6A3SLC6A4SLC6A2TACR1 | |
| SCHEMBL7305720 | 0.75 | ALDH1A1 (0.48) | OPRM1OPRL1KCNA3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673928-A1 | Novel N-(3,4-dichlorophenyl-propyl)-piperidine derivatives as selective human NK3-receptor antagonists | SANOFI (FR) | 1995-09-27 | — | — | EP | disclosed |