Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 10/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.44 |
| ▸ | AKT1 | P31749 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7266681 | 0.79 | NOTUM (0.53) | NOTUM | |
| Hydrochloric Acid SCHEMBL7439063 | 0.78 | NOTUM (0.52) | NOTUM | |
| SCHEMBL7304610 | 0.76 | NOTUM (0.52) | NOTUMCHRM3CHRM2CHRM1 | |
| SCHEMBL7550236 | 0.74 | NOTUM (0.69) | NOTUMDRD2DRD4AKT1PIK3CD | |
| SCHEMBL14294095 | 0.72 | NOTUM (1.00) | NOTUMDRD2DRD4AKT1PIK3CD | |
| SCHEMBL27852096 | 0.72 | NOTUM (0.75) | NOTUMDRD2DRD4AKT1PIK3CD | |
| Fumaric Acid SCHEMBL7304917 | 0.70 | NOTUM (0.47) | NOTUMCHRM3CHRM2CHRM1 | |
| Maleic Acid SCHEMBL7304911 | 0.70 | NOTUM (0.47) | NOTUMCHRM3CHRM2CHRM1 | |
| SCHEMBL9602684 | 0.70 | HTR6 (0.46) | NOTUM | |
| SCHEMBL4917429 | 0.70 | HTR3E (0.56) | CHRM3CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0403882-A2 | Indole derivatives and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-12-27 | — | — | EP | disclosed |