Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 2/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9601595 | 0.85 | TMEM97 (0.43) | HTR6MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL7266681 | 0.81 | NOTUM (0.53) | HTR6NOTUMHTR3ATMEM97SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7439063 | 0.80 | NOTUM (0.52) | HTR6NOTUMHTR3ATMEM97SIGMAR1 | |
| SCHEMBL9602248 | 0.78 | MEN1 (0.43) | MEN1KMT2AALDH1A1CYP3A4TSHR | |
| SCHEMBL9602391 | 0.76 | MEN1 (0.42) | MEN1KMT2AALDH1A1CYP3A4TSHR | |
| SCHEMBL9602370 | 0.74 | SMN1; SMN2 (0.48) | MEN1KMT2ATSHRHTR3AHTR3E | |
| SCHEMBL7432965 | 0.71 | HTR4 (0.50) | MEN1KMT2AHTR3ATMEM97SIGMAR1 | |
| SCHEMBL7305951 | 0.70 | NOTUM (0.55) | NOTUM | |
| SCHEMBL9602385 | 0.70 | ALDH1A1 (0.50) | ALDH1A1CYP3A4TSHRMAPK1HSD17B10 | |
| SCHEMBL10361731 | 0.70 | TMEM97 (0.46) | HTR3ATMEM97SIGMAR1HTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0247266-B1 | INDOLE DERIVATIVES HAVING AN AZABICYCLIC SIDE CHAIN, PROCESS FOR THEIR PREPARATION, INTERMEDIATES, AND PHARMACEUTICAL COMPOSITIONS | BEECHAM GROUP PLC (GB) | 1993-03-10 | — | — | EP | claimed |