Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 12/20 | 0.58 |
| ▸ | EBP | Q15125 | 2/20 | 0.44 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7305975 | 0.82 | SIGMAR1 (0.54) | SIGMAR1KCNA3 | |
| SCHEMBL7304853 | 0.81 | SIGMAR1 (0.58) | SIGMAR1KCNA3 | |
| SCHEMBL7304603 | 0.78 | SIGMAR1 (0.45) | SIGMAR1KCNA3PARP1 | |
| SCHEMBL7300904 | 0.74 | HRH3 (0.61) | SIGMAR1MEN1KMT2A | |
| SCHEMBL9632652 | 0.71 | SIGMAR1 (0.65) | SIGMAR1EBPKMT2A | |
| SCHEMBL7296057 | 0.68 | SIGMAR1 (0.61) | SIGMAR1PARP1 | |
| SCHEMBL19000986 | 0.68 | SIGMAR1 (0.60) | SIGMAR1EBP | |
| SCHEMBL466989 | 0.68 | SIGMAR1 (0.57) | SIGMAR1PARP1 | |
| SCHEMBL19001047 | 0.68 | SIGMAR1 (0.60) | SIGMAR1EBP | |
| SCHEMBL11099523 | 0.68 | SIGMAR1 (0.68) | SIGMAR1EBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5149817-A | Psychotropic agents | SHIONOGI & CO., LTD. (JP) | 1992-09-22 | — | — | US | disclosed |
| EP-0445701-A1 | Novel tetrahydropyridine derivatives | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1991-09-11 | — | — | EP | disclosed |