Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.61 |
| ▸ | DRD3 | P35462 | 3/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7305975 | 0.82 | SIGMAR1 (0.54) | HRH3SIGMAR1 | |
| SCHEMBL7304853 | 0.81 | SIGMAR1 (0.58) | SIGMAR1 | |
| SCHEMBL7304603 | 0.75 | SIGMAR1 (0.45) | DRD2SIGMAR1 | |
| SCHEMBL7306014 | 0.74 | SIGMAR1 (0.58) | SIGMAR1MEN1KMT2A | |
| SCHEMBL26108581 | 0.69 | HTR1A (0.65) | HRH3DRD3DRD2DRD4SIGMAR1 | |
| SCHEMBL26492991 | 0.69 | HTR1A (0.65) | HRH3DRD3DRD2DRD4SIGMAR1 | |
| SCHEMBL7296057 | 0.69 | SIGMAR1 (0.61) | HRH3SIGMAR1 | |
| SCHEMBL466989 | 0.68 | SIGMAR1 (0.57) | SIGMAR1 | |
| SCHEMBL9286378 | 0.68 | LMNA (0.59) | HRH3DRD3DRD2 | |
| Hydrochloric Acid SCHEMBL26108377 | 0.67 | DRD2 (0.63) | DRD3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5149817-A | Psychotropic agents | SHIONOGI & CO., LTD. (JP) | 1992-09-22 | — | — | US | disclosed |
| EP-0445701-A1 | Novel tetrahydropyridine derivatives | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1991-09-11 | — | — | EP | disclosed |