Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7304853 | 0.88 | SIGMAR1 (0.58) | SIGMAR1KCNA3 | |
| SCHEMBL7296057 | 0.85 | SIGMAR1 (0.61) | SIGMAR1HRH3KCNH2 | |
| SCHEMBL7304603 | 0.84 | SIGMAR1 (0.45) | SIGMAR1KDM4EKCNA3 | |
| SCHEMBL7306014 | 0.82 | SIGMAR1 (0.58) | SIGMAR1KCNA3 | |
| SCHEMBL7300904 | 0.82 | HRH3 (0.61) | SIGMAR1HRH3 | |
| SCHEMBL7294958 | 0.81 | QDPR (0.55) | SIGMAR1 | |
| SCHEMBL7304514 | 0.74 | SMN1; SMN2 (0.41) | SIGMAR1KDM4E | |
| SCHEMBL466989 | 0.73 | SIGMAR1 (0.57) | SIGMAR1RECQL | |
| SCHEMBL11947322 | 0.71 | SIGMAR1 (0.97) | SIGMAR1HRH3KDM4ERECQL | |
| SCHEMBL11999104 | 0.71 | HSD11B1 (0.44) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5149817-A | Psychotropic agents | SHIONOGI & CO., LTD. (JP) | 1992-09-22 | — | — | US | disclosed |
| EP-0445701-A1 | Novel tetrahydropyridine derivatives | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1991-09-11 | — | — | EP | disclosed |