Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 4/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.39 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGAV | P06756 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4806015 | 0.78 | RAB9A (0.50) | ALDH1A1MAPTITGB1ITGA5ITGB3 | |
| SCHEMBL8425241 | 0.78 | MAPT (0.48) | GFERALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL6647621 | 0.78 | LMNA (0.57) | ALDH1A1TSHRTDP1LMNACA9 | |
| SCHEMBL26099644 | 0.76 | ALDH1A1 (0.42) | GFERALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL627450 | 0.74 | MAPT (0.44) | GFERALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL7944783 | 0.74 | GRM2 (0.44) | CYP3A4MAOAMAPTFDPSLMNA | |
| SCHEMBL4678735 | 0.74 | FDPS (0.38) | GFERALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL22690199 | 0.74 | ALDH1A1 (0.41) | GFERALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL15524818 | 0.74 | HDAC1 (0.44) | ALDH1A1CYP3A4MAOBMAPTKDM4E | |
| SCHEMBL335254 | 0.74 | MEN1 (0.50) | GFERALDH1A1CYP3A4TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1050534-B1 | 2,3-methano-amino acid derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2001-12-05 | — | — | EP | disclosed |
| EP-1050534-A1 | 2,3-methano-amino acid derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-11-08 | — | — | EP | disclosed |