Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | PYGL | P06737 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PDE6D | O43924 | 1/20 | 0.33 |
| ▸ | UBE2M | P61081 | 1/20 | 0.33 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309483 | 0.87 | THRA (0.37) | THRATHRBCASP6PYGLL3MBTL1 | |
| SCHEMBL7320950 | 0.87 | THRA (0.37) | THRATHRBCASP6PYGLL3MBTL1 | |
| SCHEMBL7319354 | 0.78 | CASP6 (0.37) | CASP6L3MBTL1SMN1; SMN2PDE3BPDE3A | |
| SCHEMBL7319790 | 0.78 | PDE3B (0.35) | THRATHRBCASP6PYGLL3MBTL1 | |
| SCHEMBL7315270 | 0.77 | THRA (0.38) | THRATHRBCASP6PDE3BPDE3A | |
| SCHEMBL7321041 | 0.76 | CASP6 (0.35) | THRATHRBCASP6PYGLL3MBTL1 | |
| SCHEMBL7313849 | 0.75 | L3MBTL1 (0.39) | THRATHRBCASP6L3MBTL1SMN1; SMN2 | |
| SCHEMBL7310371 | 0.75 | PDE3B (0.42) | THRATHRBPDE3BPDE3A | |
| SCHEMBL7315054 | 0.74 | L3MBTL1 (0.38) | CASP6L3MBTL1SMN1; SMN2PDE3BPDE3A | |
| SCHEMBL7314783 | 0.74 | CASP6 (0.35) | CASP6L3MBTL1CYSLTR2CYSLTR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |