Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | PYGL | P06737 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 6/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 6/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PDE6D | O43924 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309483 | 0.88 | THRA (0.37) | THRATHRBPYGLCYP19A1CASP6 | |
| SCHEMBL7306686 | 0.87 | THRA (0.36) | THRATHRBPYGLCYP19A1CASP6 | |
| SCHEMBL10376587 | 0.83 | L3MBTL1 (0.39) | THRATHRBCASP6LTB4R2L3MBTL1 | |
| SCHEMBL10376968 | 0.81 | PDE3B (0.39) | PYGLPDE3BPDE3AGAAPTGDR2 | |
| SCHEMBL10375064 | 0.81 | PDE3B (0.39) | PYGLPDE3BPDE3AGAAPTGDR2 | |
| SCHEMBL10375880 | 0.80 | PDE3B (0.39) | PYGLPDE3BPDE3AGAAPTGDR2 | |
| SCHEMBL10375748 | 0.80 | L3MBTL1 (0.41) | THRATHRBCASP6LTB4R2L3MBTL1 | |
| SCHEMBL10375053 | 0.79 | THRA (0.40) | THRATHRBCASP6LTB4R2PDE3B | |
| SCHEMBL7310679 | 0.78 | PDE3B (0.38) | CASP6PDE3BPDE3AL3MBTL1 | |
| SCHEMBL10756286 | 0.77 | PDE3B (0.42) | PDE3BPDE3AGAAPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |