Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TACR2 | P21452 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | FCER2 | P06734 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP3 | P08254 | 2/20 | 0.37 |
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 2/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | MMP7 | P09237 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7173680 | 0.92 | ALDH1A1 (0.41) | ALDH1A1KDM4EHTTMMP8HPGD | |
| SCHEMBL7174231 | 0.90 | MMP8 (0.45) | KDM4EMMP8HSD17B10ALOX15FCER2 | |
| SCHEMBL7172650 | 0.86 | NPC1 (0.47) | ALDH1A1KDM4ESMN1; SMN2MMP3MMP1 | |
| SCHEMBL7170096 | 0.85 | FCER2 (0.50) | MMP8FCER2SMN1; SMN2MMP2MMP3 | |
| SCHEMBL7178370 | 0.84 | PPARG (0.46) | ALDH1A1KDM4ESMN1; SMN2MMP3MMP1 | |
| SCHEMBL7170637 | 0.83 | ALOX15 (0.45) | ALDH1A1KDM4EHTTMMP8HSD17B10 | |
| SCHEMBL7177458 | 0.83 | MMP8 (0.52) | ALDH1A1KDM4EHTTMMP8TACR2 | |
| SCHEMBL7174719 | 0.79 | NPC1 (0.45) | ALDH1A1KDM4ESMN1; SMN2MMP3MMP1 | |
| SCHEMBL7172740 | 0.78 | MMP3 (0.52) | ALDH1A1FCER2SMN1; SMN2MMP2MMP3 | |
| SCHEMBL7178527 | 0.77 | NPC1 (0.43) | ALDH1A1KDM4ESMN1; SMN2MMP3MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1005449-B1 | 3-ARYL-SUCCINAMIDO-HYDROXAMIC ACIDS, METHODS FOR PRODUCING SAID ACIDS AND MEDICAMENTS CONTAINING THE SAME | ROCHE DIAGNOSTICS GMBH (DE) | 2002-10-30 | — | — | EP | disclosed |
| EP-0897908-A1 | 3-Aryl-succinamido-hydroxamic acids, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1999-02-24 | — | — | EP | disclosed |