Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7303867 | 0.93 | SMN1; SMN2 (0.38) | GLAPAOXCYP1A2KDM1AALDH1A1 | |
| SCHEMBL7314634 | 0.91 | GLA (0.38) | GLATP53KDM1AALDH1A1KDM4E | |
| SCHEMBL7309061 | 0.90 | HSD17B10 (0.35) | CYP1A2ALDH1A1KDM4EHSD17B10CYP2D6 | |
| SCHEMBL7306902 | 0.88 | SMN1; SMN2 (0.40) | TP53L3MBTL1CYP1A2TERTKDM1A | |
| SCHEMBL7301320 | 0.86 | DRD2 (0.33) | GLAKDM1A | |
| SCHEMBL7317129 | 0.86 | KMT2A (0.45) | ALDH1A1MAPT | |
| SCHEMBL7308037 | 0.85 | PKM (0.35) | GLAL3MBTL1CYP1A2TERTKDM1A | |
| SCHEMBL7311142 | 0.85 | GLA (0.34) | GLAPAOXCYP1A2 | |
| SCHEMBL7313428 | 0.84 | CYP1A2 (0.37) | CYP1A2KDM1A | |
| SCHEMBL7303823 | 0.84 | PAOX (0.35) | GLAL3MBTL1PAOXCYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |