SCHEMBL7314652

SCHEMBL7314652

NS(=O)(=O)Cc1noc2ccc(Br)cc12

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 5/20 0.62
CA1 P00915 4/20 0.62
CA9 Q16790 4/20 0.62
CA12 O43570 2/20 0.62
CA7 P43166 2/20 0.62
CA14 Q9ULX7 2/20 0.62
LMNA P02545 2/20 0.62
CA5A P35218 2/20 0.62
CA3 P07451 1/20 0.62
CA4 P22748 1/20 0.62
CA6 P23280 1/20 0.62
MAOB P27338 1/20 0.62
CA13 Q8N1Q1 1/20 0.62
CA5B Q9Y2D0 1/20 0.62
CYP3A4 P08684 2/20 0.42
BLM P54132 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
MAPT P10636 2/20 0.39
PIM1 P11309 2/20 0.37
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7316076 0.86 CA2 (0.45) CA2CA1CA9CA12CA7
SCHEMBL7307801 0.81 LMNA (0.62) CA2CA1CA9CA12CA7
SCHEMBL7317657 0.81 LMNA (0.62) CA2CA1CA9CA12CA7
SCHEMBL23218521 0.78 MAPT (0.41) CA2CA1CA9CA12CA7
SCHEMBL29591789 0.78 MAPT (0.41) CA2CA1CA9CA12CA7
SCHEMBL25459999 0.78 CA2 (0.57) CA2CA1CA9CA12CA7
Zonisamide SCHEMBL35458 0.77 LMNA (1.00) CA2CA1CA9CA12CA7
Zonisamide SCHEMBL4427407 0.77 LMNA (1.00) CA2CA1CA9CA12CA7
Zonisamide SCHEMBL1816247 0.77 LMNA (1.00) CA2CA1CA9CA12CA7
SCHEMBL30895159 0.77 MAPT (0.43) CA9CA12LMNASMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4172896-A ANTICONVULSANTS DAINIPPON PHARMACEUTICAL CO., LTD. (JP) 1979-10-30 US claimed
US-4172896-A ANTICONVULSANTS DAINIPPON PHARMACEUTICAL CO., LTD. (JP) 1979-10-30 US disclosed