SCHEMBL7307904

SCHEMBL7307904

COC(=O)CN1CCN(CC2CN(CCCCC3CCN(C(=N)NC(=O)OC(C)(C)C)CC3)C(=O)O2)CC1

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 1/20 0.34
ITGB3 P05106 1/20 0.33
ITGA2B P08514 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7306733 0.98 GPR119 (0.33) GPR119ITGB3ITGA2B
SCHEMBL7316825 0.94 ITGB3 (0.34) ITGB3ITGA2B
SCHEMBL7318097 0.93 GPR119 (0.33) GPR119
SCHEMBL7306785 0.93 GPR119 (0.33) GPR119
SCHEMBL7307310 0.92 GPR119 (0.32) GPR119
SCHEMBL7309062 0.92 ITGB3 (0.34) ITGB3ITGA2B
SCHEMBL7307759 0.91 FAAH (0.33) GPR119
SCHEMBL7306190 0.90 GPR119 (0.32) GPR119
SCHEMBL7305537 0.90 ITGB3 (0.34) ITGB3ITGA2B
SCHEMBL7316594 0.90 DRD2 (0.33) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0711770-A1 Antagonists of adhesion receptors MERCK PATENT GmbH (DE) 1996-05-15 EP disclosed