Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 3/20 | 0.31 |
| ▸ | DRD3 | P35462 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7307759 | 0.98 | FAAH (0.33) | GPR119FAAHDRD2DRD3SMN1; SMN2 | |
| SCHEMBL7307310 | 0.96 | GPR119 (0.32) | GPR119FAAHDRD2DRD3NAAA | |
| SCHEMBL7310067 | 0.94 | DRD2 (0.33) | FAAHDRD2DRD3SMN1; SMN2KDM4E | |
| SCHEMBL7316594 | 0.94 | DRD2 (0.33) | GPR119FAAHDRD2DRD3 | |
| SCHEMBL7306960 | 0.93 | GPR119 (0.33) | GPR119FAAHDRD2DRD3 | |
| SCHEMBL7307904 | 0.93 | GPR119 (0.34) | GPR119 | |
| SCHEMBL7301524 | 0.93 | SIGMAR1 (0.34) | DRD2SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL7316078 | 0.91 | DRD2 (0.33) | GPR119FAAHDRD2DRD3 | |
| SCHEMBL7315701 | 0.91 | SIGMAR1 (0.34) | DRD2SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL7310946 | 0.91 | GPR119 (0.33) | GPR119FAAHDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |