Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7303812 | 0.93 | MAOA (0.36) | SMN1; SMN2ITGB3ITGA2BALDH1A1HTR2B | |
| SCHEMBL7313685 | 0.92 | ITGB3 (0.42) | SMN1; SMN2ITGB3ITGA2BHTR2BHRH3 | |
| SCHEMBL7316513 | 0.90 | SMN1; SMN2 (0.40) | SMN1; SMN2TP53ITGB3ITGA2BKDM4E | |
| SCHEMBL7313458 | 0.88 | SMN1; SMN2 (0.41) | SMN1; SMN2TP53ITGB3ITGA2BKDM4E | |
| SCHEMBL7307995 | 0.88 | GLA (0.40) | HTR2BHRH3L3MBTL1SIGMAR1 | |
| SCHEMBL7315503 | 0.87 | SMN1; SMN2 (0.38) | SMN1; SMN2TP53ITGB3ITGA2BKDM4E | |
| SCHEMBL7313041 | 0.86 | MAPK1 (0.39) | SMN1; SMN2ITGB3ITGA2BKDM4EALDH1A1 | |
| SCHEMBL7314702 | 0.86 | SMN1; SMN2 (0.38) | SMN1; SMN2ITGB3ITGA2BKDM4EALDH1A1 | |
| SCHEMBL7307029 | 0.86 | ALDH1A1 (0.47) | KDM4EALDH1A1HTR2BSIGMAR1MAPT | |
| SCHEMBL7306126 | 0.84 | HTR2B (0.40) | SMN1; SMN2TP53ITGB3ITGA2BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |