Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 9/20 | 0.50 |
| ▸ | HTR3E | A5X5Y0 | 5/20 | 0.50 |
| ▸ | HTR3B | O95264 | 5/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 5/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7301719 | 0.97 | HTR3E (0.51) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL5107516 | 0.83 | NPC1 (0.63) | NPC1RAB9APOLBSMN1; SMN2RXFP1 | |
| SCHEMBL7300915 | 0.81 | HTR3E (0.52) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7444121 | 0.81 | NPC1 (0.71) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7305234 | 0.78 | HTR3A (0.46) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7305238 | 0.78 | HTR3A (0.46) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7435902 | 0.78 | KMT2A (0.72) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7302557 | 0.71 | HTR3E (0.70) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7429752 | 0.69 | HTR3A (0.96) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL4154430 | 0.68 | EGLN1 (0.47) | NPC1RAB9ARXFP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0503844-B1 | Thienopyridine derivatives and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO KK (JP) | 1994-08-03 | — | — | EP | disclosed |
| US-5155115-A | THIENOPYRIDINE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-10-13 | — | — | US | disclosed |
| EP-0503844-A1 | Thienopyridine derivatives and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-09-16 | — | — | EP | disclosed |