Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.30 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7304525 | 0.95 | CYP1A2 (0.38) | PKMKMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL7313581 | 0.91 | ALDH1A1 (0.33) | PKMKMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL7311142 | 0.91 | GLA (0.34) | GLACYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL7314712 | 0.88 | SMN1; SMN2 (0.38) | PKMKMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL7311515 | 0.88 | MAOB (0.37) | GLACYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL7307068 | 0.86 | CYP1A2 (0.38) | KMT2AMEN1CYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL7310996 | 0.86 | PKM (0.33) | PKMGLATERTKDM1A | |
| SCHEMBL7317073 | 0.86 | MEN1 (0.33) | PKMGLAKMT2AALDH1A1MEN1 | |
| SCHEMBL7307606 | 0.85 | CHRM2 (0.43) | KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7317126 | 0.85 | GRIN1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |