Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7314586 | 0.96 | MAOB (0.37) | MAOBDAOCYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL7300811 | 0.92 | MAOB (0.37) | MAOBDAOHTR4 | |
| SCHEMBL7306138 | 0.89 | SMN1; SMN2 (0.36) | MAOBDAOSMN1; SMN2HTR4 | |
| SCHEMBL7308037 | 0.88 | PKM (0.35) | GLACYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL7313111 | 0.87 | HRH3 (0.31) | GLA | |
| SCHEMBL7313310 | 0.87 | MAOB (0.35) | MAOBDAOSMN1; SMN2HTR4 | |
| SCHEMBL7311142 | 0.86 | GLA (0.34) | GLACYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL7309143 | 0.85 | CYP1A2 (0.32) | MAOBCYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL7304525 | 0.84 | CYP1A2 (0.38) | CYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL7307606 | 0.82 | CHRM2 (0.43) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |