Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.34 |
| ▸ | REN | P00797 | 8/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | MLNR | O43193 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7317889 | 0.87 | ALDH1A1 (0.36) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7320149 | 0.85 | ALDH1A1 (0.35) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7316032 | 0.78 | SIRT3 (0.41) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7310463 | 0.77 | SIRT3 (0.39) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7308548 | 0.76 | SIRT3 (0.39) | ALDH1A1KDM4EMAPTOPRK1MEN1 | |
| SCHEMBL7318298 | 0.72 | KDM4E (0.45) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7314547 | 0.72 | KDM4E (0.46) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7315005 | 0.71 | REN (0.33) | SLC6A2RENSLC6A4SLC6A3 | |
| SCHEMBL13900800 | 0.70 | MAPT (0.55) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7317847 | 0.69 | PDE4A (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |