Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7302535 | 0.89 | HRH3 (0.34) | HRH3ALDH1A1 | |
| SCHEMBL7310999 | 0.89 | CCR5 (0.35) | CCR5LMNA | |
| SCHEMBL7314434 | 0.88 | CYP1A2 (0.35) | CCR5LMNA | |
| SCHEMBL7310309 | 0.87 | ITGB3 (0.34) | ITGB3ITGA2BCCR5ALOX15ALDH1A1 | |
| SCHEMBL7313931 | 0.84 | ITGB3 (0.31) | ITGB3ITGA2BALOX15 | |
| SCHEMBL7303836 | 0.82 | SMN1; SMN2 (0.38) | CCR5HRH3ALDH1A1 | |
| SCHEMBL7314564 | 0.81 | SMN1; SMN2 (0.33) | CCR5HRH3LMNA | |
| SCHEMBL7305616 | 0.81 | SMN1; SMN2 (0.44) | ALDH1A1 | |
| SCHEMBL7304254 | 0.81 | HRH3 (0.33) | HRH3 | |
| SCHEMBL7311851 | 0.80 | STS (0.38) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |