Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7303568 | 0.91 | ALDH1A1 (0.45) | SMN1; SMN2RECQLOPRL1OPRM1FAAH | |
| SCHEMBL7305780 | 0.90 | SMN1; SMN2 (0.43) | SMN1; SMN2RECQLOPRL1OPRM1FAAH | |
| SCHEMBL7306412 | 0.89 | SMN1; SMN2 (0.42) | SMN1; SMN2RECQLOPRL1OPRM1FAAH | |
| SCHEMBL7314659 | 0.85 | ALDH1A1 (0.43) | SMN1; SMN2RECQLALDH1A1KDM4EACHE | |
| SCHEMBL7316859 | 0.84 | ACHE (0.43) | SMN1; SMN2FAAHACHE | |
| SCHEMBL7306453 | 0.84 | ALDH1A1 (0.42) | SMN1; SMN2RECQLOPRM1ALDH1A1KDM4E | |
| SCHEMBL7310309 | 0.84 | ITGB3 (0.34) | SMN1; SMN2RECQLALDH1A1 | |
| SCHEMBL7304933 | 0.83 | ALDH1A1 (0.40) | SMN1; SMN2RECQLOPRL1OPRM1ALDH1A1 | |
| SCHEMBL7303939 | 0.82 | SMN1; SMN2 (0.44) | SMN1; SMN2OPRM1ALDH1A1TSHR | |
| SCHEMBL7313638 | 0.82 | ACHE (0.47) | ACHECHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |