Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 2/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | FPR3 | P25089 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 4/20 | 0.31 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.30 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7303836 | 0.95 | SMN1; SMN2 (0.38) | SMN1; SMN2HTR4CCR5HRH3SLC5A7 | |
| SCHEMBL7302535 | 0.90 | HRH3 (0.34) | HTR4HRH3 | |
| SCHEMBL7311024 | 0.90 | SMN1; SMN2 (0.35) | SMN1; SMN2CCR5TP53LMNABRD4 | |
| SCHEMBL7314434 | 0.89 | CYP1A2 (0.35) | SMN1; SMN2HTR4CCR5MAOBMEN1 | |
| SCHEMBL7310999 | 0.86 | CCR5 (0.35) | HTR4CCR5MEN1LMNAMAPT | |
| SCHEMBL7313310 | 0.85 | MAOB (0.35) | SMN1; SMN2HTR4FPR3FPR2MAOB | |
| SCHEMBL7305673 | 0.85 | HRH3 (0.31) | SMN1; SMN2HDAC1EHMT1HDAC6HTR4 | |
| SCHEMBL7311690 | 0.85 | SMN1; SMN2 (0.41) | SMN1; SMN2CCR5TP53L3MBTL1 | |
| SCHEMBL7306453 | 0.82 | ALDH1A1 (0.42) | SMN1; SMN2MEN1LMNAMAPTKMT2A | |
| SCHEMBL7308696 | 0.81 | ITGB3 (0.32) | CCR5HRH3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |