Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 8/20 | 0.47 |
| ▸ | THRA | P10827 | 5/20 | 0.47 |
| ▸ | BCHE | P06276 | 4/20 | 0.42 |
| ▸ | ACHE | P22303 | 4/20 | 0.42 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7312076 | 0.85 | THRB (0.45) | THRBTHRABCHEACHEVCAM1 | |
| SCHEMBL7317566 | 0.85 | THRB (0.44) | THRBTHRABCHEACHEVCAM1 | |
| SCHEMBL7321082 | 0.76 | THRA (0.47) | THRBTHRABCHEACHE | |
| SCHEMBL7316866 | 0.74 | ALDH1A1 (0.39) | NPC1HPGDTSHRRAB9ASMN1; SMN2 | |
| SCHEMBL11613382 | 0.73 | THRB (0.51) | THRBTHRA | |
| SCHEMBL10074635 | 0.72 | HTT (0.52) | THRBTHRANPC1SMN1; SMN2 | |
| SCHEMBL7312365 | 0.71 | THRA (0.46) | THRBTHRABCHEACHEEPHX2 | |
| SCHEMBL10374823 | 0.71 | BCHE (0.47) | THRBTHRABCHEACHE | |
| SCHEMBL7316914 | 0.71 | THRA (0.46) | THRBTHRABCHEACHE | |
| SCHEMBL16083524 | 0.70 | HTT (0.53) | NPC1TSHRRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |