Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 5/20 | 0.44 |
| ▸ | THRA | P10827 | 4/20 | 0.44 |
| ▸ | BCHE | P06276 | 4/20 | 0.41 |
| ▸ | ACHE | P22303 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309225 | 0.85 | THRB (0.47) | THRBTHRABCHEACHEVCAM1 | |
| SCHEMBL7312076 | 0.84 | THRB (0.45) | THRBTHRABCHEACHEALDH1A1 | |
| SCHEMBL7314747 | 0.78 | SIGMAR1 (0.38) | ALDH1A1MAPTLMNAKMT2ANPSR1 | |
| SCHEMBL7316914 | 0.77 | THRA (0.46) | THRBTHRABCHEACHEALDH1A1 | |
| SCHEMBL7308594 | 0.77 | NPSR1 (0.38) | THRBTHRAALDH1A1MAPTVCAM1 | |
| SCHEMBL7320170 | 0.75 | KMT2A (0.37) | ALDH1A1MAPTLMNAKMT2ANPSR1 | |
| SCHEMBL7315888 | 0.74 | TDP1 (0.38) | THRBTHRABCHEACHEKMT2A | |
| SCHEMBL7312450 | 0.71 | LMNA (0.44) | THRBTHRAALDH1A1MAPTLMNA | |
| SCHEMBL19548246 | 0.71 | MAPT (0.43) | ALDH1A1MAPTLMNAKMT2ANPC1 | |
| SCHEMBL7321082 | 0.71 | THRA (0.47) | THRBTHRABCHEACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |