Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | GHSR | Q92847 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | FPR1 | P21462 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309462 | 1.00 | ALDH1A1 (0.58) | ALDH1A1LMNATSHRMEN1KMT2A | |
| SCHEMBL1414267 | 0.77 | GHSR (0.51) | LMNAGHSRHDAC1HDAC6 | |
| SCHEMBL1414271 | 0.77 | GHSR (0.51) | LMNAGHSRHDAC1HDAC6 | |
| SCHEMBL7309458 | 0.77 | ALDH1A1 (0.43) | ALDH1A1LMNATSHRMEN1KMT2A | |
| SCHEMBL14102903 | 0.73 | GHSR (0.60) | GHSRMAPT | |
| SCHEMBL7314092 | 0.73 | PAX8 (0.48) | ALDH1A1LMNATSHRGHSRNPSR1 | |
| SCHEMBL7314086 | 0.73 | PAX8 (0.48) | ALDH1A1LMNATSHRGHSRNPSR1 | |
| SCHEMBL6600601 | 0.71 | GHSR (0.51) | ALDH1A1LMNATSHRMEN1KMT2A | |
| SCHEMBL17018566 | 0.71 | GHSR (0.58) | GHSR | |
| SCHEMBL7515055 | 0.70 | CTSS (0.56) | ALDH1A1LMNATSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |